Roche Sequencing & Life Science

Featured products

An end-to-end workflow for CGP featuring a 335-gene panel aligned with the FoundationOne®CDx panel design, automated by the AVENIO Edge Liquid Handler, and the FoundationOne® Analysis Platform
KAPA EvoPlus V2 Kits: Simplify library prep and reduce human error with ReadyMix formulations, enzymatic fragmentation, and tubes or plated reagents.
KAPA EvoPrep Kits are the latest high-performance, streamlined, and automation-friendly library preparation solutions from Roche. MC-US-15176
Combine the performance of hybrid-capture target enrichment with the speed and simplicity of amplicon workflows with KAPA HyperPETE (Primer Extension Target Enrichment). MC-US-10049
Walk away from manual pipetting with this all-in-one NGS pre-analytical instrument.
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    Next-Generation Sequencing (NGS) solutions

    Next-generation sequencing (NGS) is driving advances in translational and clinical research. From expanding our understanding of cancer, reproductive and developmental biology to unravelling complex microbial populations, NGS is touching all facets of human disease and well­being.

    Sample prep for NGS holds the key to unlocking the potential of every sample. Explore our integrated Roche Sample Preparation Solutions, encompassing all the steps required to convert a sample to a sequencing-ready library. We offer sample prep solutions for different sample types and sequencing applications that are proven, simple, and complete.

    Product portfolios

    Product overview

    Integrated Next-Generation Sequencing Workflow

    lab technician evaluate library prep samples

    Library Preparation

    Explore KAPA NGS library preparation kits for the highest-quality sequencing libraries, for use on lllumina sequencing platforms. Every kit leverages high-quality enzymes selected through our directed evolution technology, and is formulated in convenient, easy-to-use master mixes. Use KAPA library preparation kits for:

    • RNA-seq libraries, including rRNA depletion, mRNA enrichment, and custom depletion
    • DNA sequencing libraries, with options for enzymatic or manual DNA fragmentation
    • Challenging, degraded RNA or DNA samples

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    Target Enrichment

    Discover robust new products for target capture, with streamlined workflows that focus sequencing resources on regions of interest. Increase efficiency and depth of targeted resequencing for human genetic disease and cancer research, as well as other applications. The Roche Target Enrichment portfolio offers solutions for:

    • Human whole-exome sequencing (WES)
    • Custom-designed panels for human or nonhuman genomic regions
    • Combine the performance of hybrid-capture target enrichment with the speed and simplicity of amplicon workflows, with KAPA HyperPETE
    • Explore target enrichment technologies with our selection guide

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    AVENIO Edge System

    NGS Automation Solutions

    Maximize the potential of your lab with a trusted NGS partner


    Roche offers automated solutions across the entire next-generation sequencing (NGS) sample prep workflow, including DNA and RNA library preparation, target enrichment, and library quantification. Automation of NGS sample prep can help your lab generate more reproducible results, increase operational efficiency, and unlock more hands-off time and resources for collaborations and innovations. 

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    Oncology Assays

    Explore the AVENIO family of NGS oncology assays comprising three ctDNA and three corresponding tumor tissue assays with matched panel content for comprehensive genomic profiling, longitudinal monitoring and concordance analysis of solid tumors from tissue and plasma samples. Detect alll four mutation classes (SNVs, indels, fusions, and CNVs) in a single DNA workflow.

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    Featured Application Areas

    The AVENIO Tumor Tissue CGP Kit is an in-house next-generation sequencing (NGS) research assay that provides comprehensive genomic profiling of solid tumors from formalin-fixed paraffin-embedded (FFPE) tissue samples. Designed to match the content of the 324 gene FoundationOne® CDx panel, the kit leverages the proven technology of Foundation Medicine and Roche’s expertise to help your lab obtain reliable genomic insights.

    Start the RNA-seq process off the right way by making high-quality libraries through the streamlined, single-day workflow of the KAPA RNA HyperPrep Kits and achieve robust performance across different sample types and low-input amounts, including degraded samples.

    KAPA Target Enrichment Probes are manufactured with KAPA HiFi DNA Polymerase and demonstrate extremely high sequence fidelity, high on-target rates, and high accuracy and reproducibility.
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      For Research Use Only. Not for use in diagnostic procedures.