KAPA HyperPETE (Primer Extension Target Enrichment) is a novel hybridization capture technology designed to employ primer extension reactions to specifically capture and release target library molecules for sequencing.
This target enrichment technology preserves the performance of conventional hybridization while enabling a more efficient workflow. It has been specifically designed and optimized for small design sizes and validated to detect all major somatic variants in cfDNA, FFPE, and RNA samples, including SNVs, short indels, CNVs, MSI, and fusion transcripts (novel and known) and is especially suited for small panel oncology research applications.
The KAPA HyperPETE Portfolio includes readily available fixed-design panels for hereditary oncology, oncology hotspots, pan-cancer variants (with an MSI module), and lung cancer fusion variants. In addition, custom panels can be designed using HyperDesign, our easy-to-use online design tool.