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AVENIO Edge System

AVENIO Edge System
Discover the freedom of walk-away NGS automation

As part of Roche’s NGS Automation solutions, AVENIO Edge System is a fully automated system for library preparation, target enrichment, pooling, normalization, and quantification.  AVENIO Edge System is designed to simplify the complexity of automation and optimize lab resources, providing the freedom to walk away and work away, with confidence and trust.

  • Only 20 minutes of setup time required
  • All-in-one hardware including on-deck thermocycling and quantification
  • Ready-to-load, barcoded and modular reagents
  • Intuitive software with built-in controller and a glove-compatible touchscreen
  • No advanced automation knowledge and experience required
AVENIO Edge System Application Menu
A growing application menu of user-defined workflows

More validated Roche protocols to come in the future

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Workflow Maximum samples (Per Run) Estimated setup time (minutes)
AVENIO Edge HyperPrep or AVENIO HyperPlus DNA library preparation* 48 20
AVENIO Edge Target Enrichment with KAPA HyperExome or custom panels** 48 20
AVENIO Edge HyperCap DNA library preparation and target enrichment* 24 20
Input control - input sample quantification, normalization, and buffer exchange 96 15
Post-capture pooling and quantification – options for using external QC metrics 48 15
*These workflows use UDI primers and universal UMI or non-UMI adapters.
**The input is indexed DNA or cDNA libraries
No need to be an automation expert because it’s as easy as 1-2-3
Create, load, walk away infographic
True walk-away NGS sample prep automation
AVENIO Edge workflow

AVENIO Edge System Deck Layout

AVENIO Edge system configuration
  1. Tip waste station
  2. Thermal cycler
  3. Heater/Shaker
  4. Magnetic separation station
  5. Plate and lid waste station
  6. Tip park
  7. Sample input station
  8. Sample output station

9.  Cooling unit

10. Tube racks

11. Piercing tool

12. Reagent mini racks

13. Reagent drawer

14.  P1000, P200, P50 Filtered tips

15. Quantification plate station

16. Consumable drawer

17. Gripper fingers exchange station

18. Quantification module

19. 2D Barcode reader

20. Processing plates

21. Processing plate lids

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AVENIO Software

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    To place an order or ask a question
    Contact us

    *The AVENIO Edge System is a Class 1 US IVD and a Class A CE IVDR and is intended for downstream diagnostic applications. Reagents and kits mentioned are for Research Use Only. They are not intended for diagnostic procedures. The AVENIO Edge System can be used for Research Use Only (RUO) workflows.

    **The AVENIO Connect Software is for Research Use Only (RUO) workflows.

    ***User-defined protocols created using AVENIO Designer Software are for Research Use Only (RUO) workflows, not for use in diagnostic procedures.

    AVENIO Edge System is a Class 1 US IVD instrument and is intended for downstream diagnostic applications.

    AVENIO Edge reagents and workflows are for Research Use Only. They are not intended for diagnostic applications.

    Comprehensive Service Plan Options

    AVENIO Edge System comes with industry-leading service support from Roche, helping you to maximize your uptime and stay compliant with regulations. Our experienced service engineers are trained to keep your AVENIO Edge System calibrated and optimized.

    • Pipetting calibration is included in every installation, as well as preventive maintenance
    • With a service plan, all emergency repairs are prioritized and have a 48-hour response time guarantee*
    • Remote access connectivity allows our engineers to diagnose and resolve issues quickly in real-time
    NGS application support and training

    Our expert field and in-house support application scientists will collaborate with you to optimize your user-defined AVENIO Edge System workflows to meet your specific needs.

    • On-site user training by our field application scientists makes user experience even more effortless
    • We will help you adopt new applications that become available on the AVENIO Edge System and fine-tune the parameters for your individual workflows

    When commercially available in the US, the following service options and NGS support will be available.

     

    You choose from two simple service plan options

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    Service Features Classic Plan Premium Plan
    Annual preventive maintenance, including pipetting verification and quantification module calibration Yes Yes
    Remote email and phone technical support Yes Yes
    48-hour Field Service Response Time Yes Yes
    Unlimited emergency field service (M-F 8 - 5 ET Local) Yes Yes
    Unlimited emergency field service (weekend and holidays*)   Yes
    Certified service parts Yes Yes
    Remote access connectivity for troubleshooting Yes Yes
    On-site application support and troubleshooting Yes Yes
    On-site operator training (1 per year, 2 trainees) Yes Yes
    *48-hour response time guarantee, including weekends and Roche holidays require a Premium Service Plan.

    More information about the AVENIO Edge System service options and Roche service teams

    To place an order or ask a question
    Contact us

    AVENIO Edge System is a Class 1 US IVD instrument and is intended for downstream diagnostic applications.

    AVENIO Edge reagents and workflows are for Research Use Only. They are not intended for diagnostic applications.

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    Roche Cat. No.
    		 Description
    9283234001 AVENIO Edge Instrument
    9424962001 AVENIO Designer Software - Annual Subscription
    9539425001 AVENIO Connect Designer Light RUO - Annual Subscription

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    Roche Cat. No.
    		 Description
    		 Kit Size
    9200860001 AVENIO Edge DNA HyperPlus Kit 3 x 8 reactions
    9200878001 AVENIO Edge DNA HyperPlus Kit 3 x 24 reactions
    9200886001 AVENIO Edge DNA HyperPrep Kit 3 x 8 reactions
    9200894001 AVENIO Edge DNA HyperPrep Kit 3 x 24 reactions
    9200908001 AVENIO Edge Target Enrichment, A 3 x 8 reactions
    9200916001 AVENIO Edge Target Enrichment, A 3 x 24 reactions
    9200924001 AVENIO Edge Target Enrichment, B 3 sample runs
    9200959001 AVENIO Edge UDI Primer Mixes Plate 96 wells of primer mixes
    9200967001 AVENIO Edge HyperPure Beads 3 sample runs
    9200975001 AVENIO Edge HyperPlex UMI Adapter 3 x 8 reactions
    9200983001 AVENIO Edge HyperPlex UMI Adapter 3 x 24 reactions
    9200991001 AVENIO Edge HyperPlex Adapters 3 x 8 reactions
    9201009001 AVENIO Edge HyperPlex Adapters 3 x 24 reactions
    9200851001 AVENIO Edge Quantification Kit 3 sample runs
    9314512001 AVENIO Edge Solution A Kit 3 sample runs
    9496386001 AVENIO Edge HyperPrep with UMI, 8 reactions Library Prep and Target Enrichement 3 x 8 reactions, 3 complete KAPA HyperCap runs
    9496394001 AVENIO Edge HyperPrep without UMI, 8 reaction Library Prep and Target Enrichement 3 x 8 reactions, 3 complete KAPA HyperCap runs
    9496408001 AVENIO Edge HyperPlus with UMI, 8 reaction Library Prep and Target Enrichement 3 x 8 reactions, 3 complete KAPA HyperCap runs
    9496416001 AVENIO Edge HyperPlus without UMI, 8 reaction Library Prep and Target Enrichement 3 x 8 reactions, 3 complete KAPA HyperCap runs
    9496424001 AVENIO Edge HyperPrep with UMI, 24 reactions Library Prep and Target Enrichement 3 x 24 reactions, 3 complete KAPA HyperCap runs
    9496432001 AVENIO Edge HyperPrep without UMI 24 reactions Library Prep and Target Enrichement 3 x 24 reactions, 3 complete KAPA HyperCap runs
    9496459001 AVENIO Edge HyperPlus with UMI, 24 reactions Library Prep and Target Enrichement 3 x 24 reactions, 3 complete KAPA HyperCap runs
    9496467001 AVENIO Edge HyperPlus without UMI 24 reactions Library Prep and Target Enrichement 3 x 24 reactions, 3 complete KAPA HyperCap runs

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    Roche Cat. No.
    		 Description
    		 Package Size
    9056351001 AVENIO Edge Tip Park 16 tip parks
    8994609001 AVENIO Edge Processing Plate 50 plates
    9030956001 AVENIO Edge Quantification Plate 50 plates
    9031022001 AVENIO Edge Processing Plate Lid 50 lids
    9031049001 AVENIO Edge Liquid Waste Plate 60 plates
    9164081001 AVENIO Edge Tube, Panel 1 100 tubes
    9164090001 AVENIO Edge Tube, Panel 2 100 tubes
    9164103001 AVENIO Edge Tube, Panel 3 100 tubes
    9164111001 AVENIO Edge Tube, Panel 4 100 tubes
    9313630001 AVENIO Edge Pooling Tube 100 tubes
    9336320001 AVENIO Edge Pipette Tip, 50 uL 24 boxes of 96 tips (total of 2304 tips)
    9336346001 AVENIO Edge Pipette Tip, 200 uL 24 boxes of 96 tips (total of 2304 tips)
    9336354001 AVENIO Edge Pipette Tip, 1000 uL 24 boxes of 96 tips (total of 2304 tips)
    To place an order or ask a question
    Contact us

    The AVENIO Connect Software is for Research Use Only (RUO) workflows..

    The AVENIO Edge System is a Class 1 US IVD and a Class A CE IVDR and is intended for downstream diagnostic applications. Reagents and kits mentioned are for Research Use Only. They are not intended for diagnostic procedures. The AVENIO Edge System can be used for Research Use Only (RUO) workflows.

    AVENIO Edge System is a Class 1 US IVD instrument and is intended for downstream diagnostic applications.

    AVENIO Edge reagents and workflows are for Research Use Only. They are not intended for diagnostic applications.

    For more information about the AVENIO Edge System and/or requesting access to a virtual tour, please complete this simple form:

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    AVENIO Edge System Stories

    Even the most advanced genomics laboratories are constrained by labor-intensive, time-consuming NGS library preparation workflows; as a result, many labs now rely on automation. However, the initial adoption of automated NGS workflows on a liquid handling system typically requires a unique combination of experience in advanced automation and script writing, and the optimization and maintenance of these systems can require a great deal of time and other resources.

    Now, with AVENIO Edge System for automated NGS, everyone in the lab can benefit from easy-to-use, automated NGS that simplifies the complexity of library prep automation while freeing up hours of time for other projects.

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    Sarah is a lab technician who is responsible for performing many complex projects that require her full attention, including NGS library prep– not one of her favorite tasks. Sarah would love to automate her NGS workflows, but she just doesn’t have time to learn a complicated new system and optimize the workflows.

    Nate is a lab manager who orchestrates the day-to-day activities in the lab, prioritizes projects, and oversees general lab operations. Although he manages the laboratory staff, including Sarah, he sometimes joins them at the bench -- especially when project deadlines are looming. Nate is also responsible for evaluating new technologies to determine if they are a good fit for his lab, as well as ensuring that existing instrumentation is maintained.

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    Kevin is an in-house automation engineer who has many years of robotics experience. He supports all the labs in his organization that operate automated liquid handlers, including Nate’s. An important part of his job is to work with both the automation vendors and the lab operators to implement and optimize new automated solutions. Kevin is an expert in what he does, but unfortunately he is the only automation specialist in the organization and there are many complex projects that require the support of an automation expert.

    AVENIO Edge System is a Class 1 US IVD instrument and is intended for downstream diagnostic applications.

    AVENIO Edge reagents and workflows are for Research Use Only. They are not intended for diagnostic applications.