Roche Sequencing & Life Science

NGS

Next-Generation Sequencing

Reagents and instruments for NGS sample prep, as well as qPCR and dPCR

Featured products

KAPA EvoPlus V2 Kits: Simplify library prep and reduce human error with ReadyMix formulations, enzymatic fragmentation, and tubes or plated reagents.

KAPA EvoPrep Kits

KAPA EvoPrep Kits are the latest high-performance, streamlined, and automation-friendly library preparation solutions from Roche. MC-US-15176

KAPA HyperPETE Panels

Combine the performance of hybrid-capture target enrichment with the speed and simplicity of amplicon workflows with KAPA HyperPETE (Primer Extension Target Enrichment). MC-US-10049

AVENIO Tumor Tissue CGP Kit

Designed to match the content of the 324 gene FoundationOne® CDx panel, the assay detects four classes of genomic alterations as well as genomic signatures: TMB, MSI, LOH. MC-US-11350

AVENIO Edge System

Walk away from manual pipetting with this all-in-one NGS pre-analytical instrument.

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Next Generation Sequencing (NGS) solutions

Next-generation sequencing (NGS) is driving advances in translational and clinical research. From expanding our understanding of cancer, reproductive and developmental biology to unravelling complex microbial populations, NGS is touching all facets of human disease and wellbeing.

Sample prep for NGS holds the key to unlocking the potential of every sample. Explore our integrated Roche Sample Preparation Solutions, encompassing all the steps required to convert a sample to a sequencing-ready library. From sample collection to library quantification, we offer sample prep solutions for different sample types and sequencing applications that are proven, simple, and complete.

Product overview

Integrated Next-Generation Sequencing Workflow

Nucleic Acid Extraction

The Roche family of MagNA Pure Systems dramatically reduces the handling errors associated with manual techniques by automating and simplifying nucleic acid extraction.

Sample QC

Determine the probability of sequencing success for low quality samples prior to library construction using qPCR-based technology. Explore a qPCR-based NGS library quantification and quality control kit for reliable assessment of library concentration and quality in a single assay.

Library Preparation

KAPA NGS Library Preparation Kits include streamlined kits for DNA & RNA, and deliver high-quality sequencing libraries suitable for Illumina platforms.

Target Enrichment

Enrich your target regions of interest using KAPA HyperCap and KAPA HyperPETE Workflows.

Library Quantification

Quantify NGS libraries reliably and accurately with DNA standards and qPCR primers produced with stringent quality control. Amplify diverse DNA fragments with comparable efficiency and maximum lot-to-lot consistency using the KAPA Library Quantification Kits containing KAPA SYBR FAST DNA Polymerase engineered using our directed evolution technology. MC-US-01271

Library Preparation

Explore KAPA NGS library preparation kits for the highest-quality sequencing libraries, for use on lllumina sequencing platforms. Every kit leverages high-quality enzymes selected through our directed evolution technology, and is formulated in convenient, easy-to-use master mixes. Use KAPA library preparation kits for:

RNA-seq libraries, including rRNA depletion, mRNA enrichment, and custom depletion
DNA sequencing libraries, with options for enzymatic or manual DNA fragmentation
Challenging, degraded RNA or DNA samples

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Target Enrichment

Discover robust new products for target capture, with streamlined workflows that focus sequencing resources on regions of interest. Increase efficiency and depth of targeted resequencing for human genetic disease and cancer research, as well as other applications. The Roche Target Enrichment portfolio offers solutions for:

Human whole-exome sequencing (WES)
Custom-designed panels for human or nonhuman genomic regions
Combine the performance of hybrid-capture target enrichment with the speed and simplicity of amplicon workflows, with KAPA HyperPETE
Explore target enrichment technologies with our selection guide

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AVENIO Edge System

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NGS Automation Solutions

Maximize the potential of your lab with a trusted NGS partner

Roche offers automated solutions across the entire next-generation sequencing (NGS) sample prep workflow, including DNA and RNA library preparation, target enrichment, and library quantification. Automation of NGS sample prep can help your lab generate more reproducible results, increase operational efficiency, and unlock more hands-off time and resources for collaborations and innovations.

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Oncology Assays

Explore the AVENIO family of NGS oncology assays comprising three ctDNA and three corresponding tumor tissue assays with matched panel content for comprehensive genomic profiling, longitudinal monitoring and concordance analysis of solid tumors from tissue and plasma samples. Detect alll four mutation classes (SNVs, indels, fusions, and CNVs) in a single DNA workflow.

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Featured Application Areas

Get deeper genomic insights about solid tumors

The AVENIO Tumor Tissue CGP Kit is an in-house next-generation sequencing (NGS) research assay that provides comprehensive genomic profiling of solid tumors from formalin-fixed paraffin-embedded (FFPE) tissue samples. Designed to match the content of the 324 gene FoundationOne^® CDx panel, the kit leverages the proven technology of Foundation Medicine and Roche’s expertise to help your lab obtain reliable genomic insights.

KAPA Target Enrichment Better by Design

KAPA Target Enrichment Probes are manufactured with KAPA HiFi DNA Polymerase and demonstrate extremely high sequence fidelity, high on-target rates, and high accuracy and reproducibility.

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How to Order

Includes custom quotes and pricing specific to your account, a quick order form for rapid and efficient order submission, and personalized promotions and content.

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For Research Use Only. Not for use in diagnostic procedures.

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Featured products

Library Preparation

Target Enrichment

NGS Automation Solutions

Maximize the potential of your lab with a trusted NGS partner

Oncology Assays

Featured Application Areas

How to Order

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Roche Sequencing & Life Science

NGS

Next-Generation Sequencing

Featured products

Product portfolios

Integrated Next-Generation Sequencing Workflow

Library Preparation

Target Enrichment

NGS Automation Solutions

Maximize the potential of your lab with a trusted NGS partner

Oncology Assays

Featured Application Areas

How to Order