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Product Listing

Whole-Exome Sequencing

KAPA HyperExome Probes and Workflows

Whole-exome Sequencing (WES) enables in-depth, targeted interrogation of genomic coding regions while conserving sequencing resources compared to whole-genome sequencing (WGS). Rely on Roche Sequencing workflows—from automated DNA extraction through library preparation, exome enrichment, and accurate library quantification—to provide you with high-quality exome results on Illumina ® sequencing platforms.

From sample to sequencing, with support at every step

 

  • Automated DNA extraction in as little as 30 minutes
  • Streamlined, single-tube, PCR-free library construction with high conversion rates
  • Enrichment of exonic regions with KAPA HyperExome V2
  •  Accurate, sensitive quantification for reliable library pooling and clustering
  • Integrated service and support throughout the workflow

KAPA HyperExome V2 Probes

Deliver superior coverage of recent versions of ACMGv3.1, RefSeq, CCDS, ClinVar, Ensembl, and COSMIC genomic databases. This design also reduces sequencing requirements, with a compact capture target of 43.2 Mb covering 37.5 Mb of key content.

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KAPA HyperExome V1 Probes

Provides comprehensive coverage and enhanced uniformity with low sequencing requirements. Based on the GRCh38/hg38 human genome assembly, the comprehensive-yet-compact panel efficiently covers content in CCDS, RefSeq, ENSEMBL,and ClinVar.

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For Research Use Only. Not for use in diagnostic procedures.

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