KAPA HyperCap Workflow

KAPA HyperCap Workflow produces high-quality, sequencing-ready libraries in less than two days by combining the high conversion rate of KAPA EvoPrep, KAPA HyperPrep, KAPA EvoPlus V2, or KAPA HyperPlus, with efficient, uniform KAPA Target Enrichment probes in a streamlined, single-vendor supported workflow. KAPA Universal Adapters and KAPA UDI primer mixes increase library conversion efficiency while mitigating index hopping, and single-sided size selection reduces workflow time while increasing library complexity and yields.

• Achieve greater success with low-input and poor-quality samples with KAPA EvoPrep, KAPA HyperPrep, KAPA EvoPlus V2, or KAPA HyperPlus Library Preparation Kits
• Explore options to further reduce turnaround times with shorter hybridization steps using Roche's KAPA HyperExome V2 panel
• Automate the entire KAPA HyperCap Workflow without the need for a SpeedVac™—now with all hybridization and bead wash steps at 55ºC
• Reduce workflow complexity and hands-on time with KAPA Universal Enhancing Oligos, eliminating the need for adapter-matched blocking oligos
• Multiplex up to 16 samples in the same capture, and potentially post-capture multiplex more samples in the same sequencing lane, with KAPA Universal Adapters with KAPA UDI Primer Mixes (384 unique pairs).