KAPA Target Enrichment Custom Panels

Combining more than a decade of probe-design experience with an improved manufacturing process, new KAPA HyperChoice Probes (for human designs) and KAPA HyperExplore Probes (for nonhuman designs) are fully customizable target enrichment panels for hybridization-based capture before next-generation sequencing. Answer your most challenging research questions with probes manufactured using KAPA HiFi DNA polymerase and validated by NGS.

Easily design customized probe pools with our HyperDesign software, then combine them with our KAPA EvoPrep or KAPA EvoPlus library preparation and KAPA Target Enrichment kits to:

• Reduce sequencing costs and save time with superior capture uniformity
• Reliably enrich challenging, previously inaccessible genomic regions
• Streamline targeted enrichment using the updated KAPA HyperCap Workflow v3, driven by KAPA EvoPrep or KAPA EvoPlus library preperation kits

Achieve better coverage, higher uniformity, and low PCR duplication rates (Table 1, Figure 1) with high-fidelity KAPA Target Enrichment probe panels designed using the expertise of HyperDesign (HyperDesign.com).

The new online, user-friendly HyperDesign tool builds on two decades of in silico design experience to select probe panels that achieve deeper, more uniform downstream sequencing coverage with fewer sequencing reads—even across difficult-to-capture regions.

Design your new probe panel in 4 easy steps:

1. Select your organism of interest and name your design
2. Add your targets by uploading gene names, bed files, or genomic coordinates—or choose from a broad list of commonly used gene identifiers
3. Fine-tune your inputs, review your targets, and confirm your results
4. Submit your design for probe selection

Design your custom panel