1. Roche Sequencing
  2. Library Preparation
  3. Library Preparation Accessories
  4. KAPA HyperPure Beads

KAPA HyperPure Beads

Overview

As a part of the dynamic Roche Sample Prep Solutions portfolio, KAPA HyperPure Beads offer a tunable and highly consistent solution for a size selection and reaction purification in DNA library construction workflows for next-generation sequencing.

  • Achieve high recovery of DNA across a wide range of input amounts and input quality
  • Implement tunable size selection at multiple stages of DNA library construction
  • Reduce sequencing costs and maximize library diversity with improved bead wash efficiency
  • Remove undesirable reaction components with fast bead cleanup steps
  • Choose from five pack sizes for workflow flexibility

Product Highlights

High DNA recovery

  • Compatible with all KAPA HyperPrep and KAPA HyperPlus Kits for DNA library preparation
  • Obtain high yields of unfragmented DNA prior to library construction compared to the market leader (Supplier A)
  • Recover degraded DNA with efficiency comparable to Supplier A

KAPA HyperPure Beads provide superior recovery performance to Supplier A in DNA workflows.

Tunable, flexible, size selection

  • Perform size selection at multiple steps throughout DNA library preparation workflows
  • Optimize insert fragment size to meet specific application needs

KAPA HyperPure Beads provide tunable size selection of doublestranded DNA. At each step of the KAPA HyperPrep library preparation workflow, DNA was subjected to double-sided size selection using various parameters and then analyzed for size distribution with a Bioanalyzer 2100 High Sensitivity Kit. Each panel shows the resulting fragment size distribution compared to same-stage DNA that was not size-selected. DNA concentrations were normalized prior to loading onto the BioAnalyzer.

Research Use Only. Not for use in diagnostic procedures.
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