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AVENIO ctDNA Targeted Kit V2

For Research Use Only. Not for use in diagnostic procedures.
AVENIO ctDNA targeted kit

Overview

 

The AVENIO ctDNA Targeted Kit V2 is a next-generation sequencing (NGS) liquid biopsy assay that contains 17 genes, including those in U.S. National Comprehensive Cancer Network (NCCN) Guidelines.1 The Targeted panel may be used for pan-cancer research applications, but is specially optimized for lung cancer and colorectal cancer (CRC) research. The AVENIO ctDNA Targeted Kit V2 is an efficient tumor profiling solution.

 

Features and Benefits

 

  • Includes genes in the U.S. National Comprehensive Cancer Network (NCCN) Guidelines1
  • All four mutation classes (SNVs, indels, fusions and CNVs) in a single assay
  • Exceptional analytical performance supported by integrated digital error suppression (iDES) strategies combining molecular barcodes with in silico error suppression techniques2,3
  • Includes reagents, bioinformatics and software
  • Streamlined, end-to-end research workflow from extraction to analysis and reporting in five days

Exceptional Performance3

AVENIO ctDNA Analysis Kit V2 chart
AVENIO ctDNA and Tumor Tissue Targeted Panel V2 Gene List

The AVENIO family of NGS oncology assays

The AVENIO ctDNA Targeted Kit V2 is a part of the AVENIO family of NGS oncology research assays that include three ctDNA and three corresponding tumor tissue assays. By using the wider family of AVENIO assays, labs can obtain detailed molecular findings across all four mutation classes from plasma or tissue samples.

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References

  1. National Comprehensive Cancer Network. Accessed August 2, 2023
  2. Newman AM, Bratman SV, To J, et al. An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. Nature Medicine. 2014;20(5):548–554 doi:10.1038/nm.3519
  3. Data on file with Roche.

Specifications

  • Panel size

    81kb

  • Sample size

    4 ml of plasma

  • cfDNA input

    10-50 ng

  • Reactions per kit

    16

  • Turn-around time

    5 days from extraction to results

To ask a question or to speak to a Roche representative
Contact us