Sequencing using nanopores—tiny apertures on the cell membrane—enables the sequencing of single DNA molecules. A semiconductor-based electronic detection system detects the unique electrical signals of different molecules as they pass through the nanopore. This sequencing technology offers several advantages over existing modalities that use optical or pH change methods to detect DNA sequences (1) :
- Flexibility and versatility
- Both short and longer read lengths
- Ultra-rapid data generation and analysis
- Cost-effectiveness
SBX can be paired with the nanopore and electronic sensor technology to enable high throughput, high accuracy, and cost-effective sequencing with faster time-to-data.