Product Listing

Hybridization-Based Target Enrichment


Targeted sequencing enables researchers to enrich specific genes, exons and/or other genomic regions to allow sequencing reads to be dedicated to only the regions that are of interest, which results in time and cost savings.1 To enrich specific target regions for next-generation sequencing (NGS) and bioinformatic analysis, hybridization or capture-based target enrichment is a method frequently used. This technique can be applied to single nucleotide polymorphism (SNP) detection, insertion/deletion (indel) detection, copy number variation (CNV) detection and structural variation detection.

KAPA HyperCap Target Enrichment Portfolio

Now available is Roche’s new KAPA HyperCap Target Enrichment Portfolio - KAPA HyperExome, KAPA HyperChoice and KAPA HyperExplore probes. Our industry-leading selection of probes will now offer higher performance, higher probe fidelity and in-solution hybridization capture, as well as longer probes with fixed length.

Benefits of KAPA HyperCap Target Enrichment Probes
  • Better capture uniformity
  • Lower duplicate rate
  • Higher target coverage
  • Customer design expertise


  1. Kozarewa et al. Curr Protoc Mol Biol., 2015. Overview of target enrichment strategies. 


The KAPA HyperExome probes replaced SeqCap EZ Prime Exome Probes, which is no longer being supported as of March 2022.

For Research Use Only. Not for use in diagnostic procedures.

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