navify^® Mutation Profiler

navify Mutation Profiler is a cloud-based next-generation sequencing (NGS) tertiary analysis and reporting solution that helps labs and researchers confidently, clearly, and efficiently interpret the significance of mutations. It streamlines the interpretation, annotation, and reporting of oncology sequencing data with an intuitive interface and the comprehensive Roche knowledge base—providing access to targeted therapies and clinical trials to support precision medicine and research. By reducing curation time and automating report generation, navify Mutation Profiler increases lab efficiency and enables scalability.

• Accurate and efficient interpretation of the significance of mutations
• Reduces time to report with an easy-to-use interface
• Secured - ISO, HIPAA and GDPR-EU compliant system
• Enables shared lab analytics and customized variant classification and annotations
• Option to share and access anonymized data to aid in interpretation
• Flexible report customization to better serve reporting needs
• Secure transfer of reports to navify Clinical Hub and EMR systems

Roche knowledge base

• Provides in-depth content curation for:
  • NGS assays from any platform for solid tumor, hematologic and liquid biopsy samples
  • A wide range of commercially available NGS panels including  research panels such as the 324-gene AVENIO Tumor Tissue CGP Kit*
  • Genomic TMB & MSI
• Localized therapies and clinical trial options for +140 countries
• Informs on implications of variant combinations for characterizing disease
• Undergoes a rigorous, multi-step data quality curation process