AVENIO Edge System

AVENIO Edge System
Walk away from manual pipetting

Part of the Roche NGS Automation solution, the AVENIO Edge System* simplifies the inherent complexities of NGS workflows by automating key steps thereby optimizing lab resources, providing the freedom to walk away with confidence.
 

The AVENIO Edge System is an all-in-one, pre-analytical platform that minimizes manual touchpoints, includes ready-to-load reagents, validated research protocols, on-board QC capabilities and intuitive software to manage your NGS sample workflows like never before.

Simplify NGS with the AVENIO Edge System

This two minute video highlights the features and benefits of the AVENIO Edge System, including:

  • Intuitive system software for sample and consumables tracking
  • On-deck capabilities including thermal cycling, quantification and pooling
  • Plug-and-play, barcoded reagents* - powered by KAPA
  • Efficient, consistent, high-quality results
  • 20 minutes to "set-it-and-forget-it"
  • No specialized knowledge or experience required
AVENIO Edge workflow
Components and run setup

Pierre-Luc Janvier, Senior Manager System development walks through the features and benefits of the AVENIO Edge System. (7:34)

AVENIO Edge System Deck Layout

AVENIO Edge system configuration
  1. Tip waste station
  2. Thermal cycler
  3. Heater/Shaker
  4. Magnetic separation station
  5. Plate and lid waste station
  6. Tip park
  7. Sample input station
  8. Sample output station

9.  Cooling unit

10. Tube racks

11. Piercing tool

12. Reagent mini racks

13. Reagent drawer

14.  P1000, P200, P50 Filtered tips

15. Quantification plate station

16. Consumable drawer

17. Gripper fingers exchange station

18. Quantification module

19. 2D Barcode reader

20. Processing plates

21. Processing plate lids

To place an order or ask a question
Contact us

*The AVENIO Edge System is a Class 1 US IVD and a Class A CE IVDR and is intended for downstream diagnostic applications. Reagents and kits mentioned are for Research Use Only. They are not intended for diagnostic procedures. The AVENIO Edge System can be used for Research Use Only (RUO) workflows.

**The AVENIO Connect Software is for Research Use Only (RUO) workflows.

***User-defined protocols created using AVENIO Designer Software are for Research Use Only (RUO) workflows, not for use in diagnostic procedures.

General

  • Configuration

    Floor model

  • Throughput per run

    1 - 48 samples for library prep and target enrichment

  • Runtime

    Up to 31 hrs (including 16 hrs hybridization time)

  • Setup time

    Approximately 15 mins prior to run

  • Inventory check

    Pre-run consumable list. Pre-run check for empty positions and incorrectly placed items

  • Quality control on deck

    Fluorescence-based quantifiction method

  • Barcodes

    2D imager scans for 2D and 1D barcodes

  • Regulatory label

    US-IVD, CE-IVD

Kits and applications

  • Reagent design

    Pre-filled, barcoded, ready-to-use. Reagent kits are optimized for 3 runs.*

  • Sample type

    Extracted DNA samples

  • Workflow

    Library preparation + Hybridization-based target enrichment

AVENIO Edge System Application Menu
A growing application menu of user-defined workflows


More validated Roche protocols to come in the future

Workflow Maximum samples (Per Run) Estimated setup time (minutes)
AVENIO Edge HyperPrep or AVENIO HyperPlus DNA library preparation** 48 20
AVENIO Edge Target Enrichment with KAPA HyperExome or custom panels*** 48 20
AVENIO Edge HyperCap DNA library preparation and target enrichment** 24 20
Input control - input sample quantification, normalization, and buffer exchange 96 15
Post-capture pooling and quantification – options for using external QC metrics 48 15

Software and connectivity

  • Traceability

    21 CFR part 11 compliant (subsection B), audit trail, process monitoring, user guidance

  • Data export

    CSV, XML and PDF run exports. Sample input in .csv format

  • Interfaces

    2 external USB ports and 1 network port

  • Connectivity

    AVENIO Connect Software or HL7 LIS connection, Roche remote service solution

To place an order or ask a question
Contact us

* For Research Use Only. Not for use in diagnostic procedures.

** These workflows use UDI primers and universal UMI or non-UMI adapters.

*** The input is indexed DNA or cDNA libraries

The AVENIO Connect Software is for Research Use Only (RUO) workflows.

The AVENIO Edge System is a Class 1 US IVD and a Class A CE IVDR and is intended for downstream diagnostic applications.
Reagents and kits mentioned are for Research Use Only. They are not intended for diagnostic procedures.
The AVENIO Edge System can be used for Research Use Only (RUO) workflows.

Roche Cat. No.
Description
9283234001 AVENIO Edge Instrument
9424962001 AVENIO Designer Software - Annual Subscription
9345442001 AVENIO Connect CGP Kit RUO - Annual Subscription
9539425001 AVENIO Connect Designer Light RUO - Annual Subscription
Roche Cat. No.
Description
Kit Size
9200860001 AVENIO Edge DNA HyperPlus Kit 3 x 8 reactions
9200878001 AVENIO Edge DNA HyperPlus Kit 3 x 24 reactions
9200886001 AVENIO Edge DNA HyperPrep Kit 3 x 8 reactions
9200894001 AVENIO Edge DNA HyperPrep Kit 3 x 24 reactions
9200908001 AVENIO Edge Target Enrichment, A 3 x 8 reactions
9200916001 AVENIO Edge Target Enrichment, A 3 x 24 reactions
9200924001 AVENIO Edge Target Enrichment, B 3 sample runs
9200959001 AVENIO Edge UDI Primer Mixes Plate 96 wells of primer mixes
9200967001 AVENIO Edge HyperPure Beads 3 sample runs
9200975001 AVENIO Edge HyperPlex UMI Adapter 3 x 8 reactions
9200983001 AVENIO Edge HyperPlex UMI Adapter 3 x 24 reactions
9200991001 AVENIO Edge HyperPlex Adapters 3 x 8 reactions
9201009001 AVENIO Edge HyperPlex Adapters 3 x 24 reactions
9200851001 AVENIO Edge Quantification Kit 3 sample runs
9314512001 AVENIO Edge Solution A Kit 3 sample runs
9496386001 AVENIO Edge HyperPrep with UMI, 8 reactions Library Prep and Target Enrichement 3 x 8 reactions, 3 complete KAPA HyperCap runs
9496394001 AVENIO Edge HyperPrep without UMI, 8 reaction Library Prep and Target Enrichement 3 x 8 reactions, 3 complete KAPA HyperCap runs
9496408001 AVENIO Edge HyperPlus with UMI, 8 reaction Library Prep and Target Enrichement 3 x 8 reactions, 3 complete KAPA HyperCap runs
9496416001 AVENIO Edge HyperPlus without UMI, 8 reaction Library Prep and Target Enrichement 3 x 8 reactions, 3 complete KAPA HyperCap runs
9496424001 AVENIO Edge HyperPrep with UMI, 24 reactions Library Prep and Target Enrichement 3 x 24 reactions, 3 complete KAPA HyperCap runs
9496432001 AVENIO Edge HyperPrep without UMI 24 reactions Library Prep and Target Enrichement 3 x 24 reactions, 3 complete KAPA HyperCap runs
9496459001 AVENIO Edge HyperPlus with UMI, 24 reactions Library Prep and Target Enrichement 3 x 24 reactions, 3 complete KAPA HyperCap runs
9496467001 AVENIO Edge HyperPlus without UMI 24 reactions Library Prep and Target Enrichement 3 x 24 reactions, 3 complete KAPA HyperCap runs
Roche Cat. No.
Description
Package Size
9056351001 AVENIO Edge Tip Park 16 tip parks
8994609001 AVENIO Edge Processing Plate 50 plates
9030956001 AVENIO Edge Quantification Plate 50 plates
9031022001 AVENIO Edge Processing Plate Lid 50 lids
9031049001 AVENIO Edge Liquid Waste Plate 60 plates
9164081001 AVENIO Edge Tube, Panel 1 100 tubes
9164090001 AVENIO Edge Tube, Panel 2 100 tubes
9164103001 AVENIO Edge Tube, Panel 3 100 tubes
9164111001 AVENIO Edge Tube, Panel 4 100 tubes
9313630001 AVENIO Edge Pooling Tube 100 tubes
9336320001 AVENIO Edge Pipette Tip, 50 uL 24 boxes of 96 tips (total of 2304 tips)
9336346001 AVENIO Edge Pipette Tip, 200 uL 24 boxes of 96 tips (total of 2304 tips)
9336354001 AVENIO Edge Pipette Tip, 1000 uL 24 boxes of 96 tips (total of 2304 tips)
To place an order or ask a question
Contact us

The AVENIO Connect Software is for Research Use Only (RUO) workflows..

The AVENIO Edge System is a Class 1 US IVD and a Class A CE IVDR and is intended for downstream diagnostic applications. Reagents and kits mentioned are for Research Use Only. They are not intended for diagnostic procedures. The AVENIO Edge System can be used for Research Use Only (RUO) workflows.