AVENIO Edge System

AVENIO Edge System
Walk away from manual pipetting

Part of the Roche NGS Automation solution, the AVENIO Edge System* simplifies the inherent complexities of NGS workflows by automating key steps thereby optimizing lab resources, providing the freedom to walk away with confidence. 
 

The AVENIO Edge System is an all-in-one, pre-analytical platform that minimizes manual touchpoints, includes ready-to-load reagents, validated research protocols, on-board QC capabilities and intuitive software to manage your NGS sample workflows like never before.

Customer testimonial

Queen's University Belfast shares how AVENIO Edge System got their ACTIONED Project on track.

Queen's University Belfast summary video

This 2:22 video gives a brief overview of how the AVENIO Edge System brought a major project back online.

Queen's University Belfast extended video

In 7 minutes, learn how Queen's University Belfast used the AVENIO Edge System to clear a backlog of samples in record time for a mission critical project.

A tale of two labs

Watch this 4:30 video to see how labs can reconceptualize the work week with the AVENIO Edge through:

  • Roche's centralized solution to the NGS sample preparation automation challenge
  • Minimal interaction = On-deck thermal cycling, quantification and pooling
  • Pre-made, plug-and-play, barcoded reagents (no pipetting)* - powered by KAPA
  • 20 minutes to "set-it-and-forget-it"
  • Up to 36 hours unattended run time (library preparation and target enrichment in one touch)
NGS sample prep - automated with the AVENIO Edge System vs manual
AVENIO Edge workflow
AVENIO Edge System features and benefits

Components and run setup

Pierre-Luc Janvier, Senior Manager System development walks through the features and benefits of the AVENIO Edge System. (7:34)

AVENIO Edge System deck layout

AVENIO Edge system configuration
  1. Tip waste station
  2. Thermal cycler
  3. Heater/Shaker
  4. Magnetic separation station
  5. Plate and lid waste station
  6. Tip park
  7. Sample input station
  8. Sample output station

9.  Cooling unit

10. Tube racks

11. Piercing tool

12. Reagent mini racks

13. Reagent drawer

14.  P1000, P200, P50 Filtered tips

15. Quantification plate station

16. Consumable drawer

17. Gripper fingers exchange station

18. Quantification module

19. 2D Barcode reader

20. Processing plates

21. Processing plate lids

To place an order or ask a question
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*The AVENIO Edge System is a Class 1 US IVD and a Class A CE IVDR and is intended for downstream diagnostic applications. Reagents and kits mentioned are for Research Use Only. They are not intended for diagnostic procedures. The AVENIO Edge System can be used for Research Use Only (RUO) workflows.

**User-defined protocols created using AVENIO Designer Software are for Research Use Only (RUO) workflows, not for use in diagnostic procedures.

General

  • Configuration

    Floor model

  • Throughput per run

    1 - 48 samples for library prep and target enrichment

  • Runtime

    Up to 31 hrs (including 16 hrs hybridization time)

  • Setup time

    Approximately 15 mins prior to run

  • Inventory check

    Pre-run consumable list. Pre-run check for empty positions and incorrectly placed items

  • Quality control on deck

    Fluorescence-based quantifiction method

  • Barcodes

    2D imager scans for 2D and 1D barcodes

  • Regulatory label

    US-IVD, CE-IVD

Kits and applications

  • Reagent design

    Pre-filled, barcoded, ready-to-use. Reagent kits are optimized for 3 runs.*

  • Sample type

    Extracted DNA samples

  • Workflow

    Library preparation + Hybridization-based target enrichment

AVENIO Edge System Application Menu

A growing application menu of user-defined workflows


More validated Roche protocols to come in the future

Software and connectivity

  • Traceability

    21 CFR part 11 compliant (subsection B), audit trail, process monitoring, user guidance

  • Data export

    CSV, XML and PDF run exports. Sample input in .csv format

  • Interfaces

    2 external USB ports and 1 network port

  • Connectivity

    HL7 LIS connection, Roche remote service solution

To place an order or ask a question
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* For Research Use Only. Not for use in diagnostic procedures.

** These workflows use UDI primers and universal UMI or non-UMI adapters.

*** The input is indexed DNA or cDNA libraries

The AVENIO Edge System is a Class 1 US IVD and a Class A CE IVDR and is intended for downstream diagnostic applications.

Reagents and kits mentioned are for Research Use Only. They are not intended for diagnostic procedures.
The AVENIO Edge System can be used for Research Use Only (RUO) workflows.

To place an order or ask a question
Contact us

The AVENIO Edge System is a Class 1 US IVD and a Class A CE IVDR and is intended for downstream diagnostic applications. Reagents and kits mentioned are for Research Use Only. They are not intended for diagnostic procedures. The AVENIO Edge System can be used for Research Use Only (RUO) workflows.