Sequencing by expansion (SBX) is set to shape the future of NGS with the speed, accuracy, scalability and flexibility it offers. With the advent of this novel technology comes the need for tools equipped to maximize its value. Here you’ll find access to data sets, cutting edge analysis tools and supporting resources to enable the future of NGS.
SBX data analysis resources
Webinar
SBX-D analysis webinar
September 10, 2025
An in-depth exploration of SBX-Duplex data and whole-genome germline small variant calling to support the release of a publicly available WGS SBX-D data set.
Enabling the future of NGS with SBX-optimized open-source (XOOS) analysis tools
The SBX technology and analysis tools are in development. The content of this material reflects current study results and/or design goals.
Access the data set
Create your account to access the whole genome sequencing SBX-D genome in a bottle (GIAB) data set.
Analysis tool resources

XOOS small variant caller
XOOS analysis tools, including XOOS SVC, are hosted by Roche on Github

Analysis tool documentation
Supporting documentation for XOOS analysis tools, including XOOS SVC, is hosted by Roche on Gitbook.
