Design Share overview

Design Share panels are NGS Target Enrichment designs developed by Roche scientists and in collaboration with leading researchers around the world.

Featuring pre-designed content from research experts, Roche’s probe design expertise and performance data, the Design Share panels are offering you the benefit of a confident and convenient entrance into the NGS Target Enrichment space. They are also fully customizable, allowing you the flexibility to add or remove content, to better suit your research needs.

With our dedicated page for Design Share, we make it simple to access pre-designed target enrichment panels for NGS.  


Features and benefits of Design Share Panels

Target enrichment designs shared by researchers across the world, built using our proven probe design algorithms, are continuously expanding and serve to suit the needs of demanding research applications, including human oncology and genetics and other research applications.  

An integrated approach to sample preparation for applications such as targeted sequencing, encompassing all the steps required to convert a sample to a sequencing-ready library, is beneficial in your research, considering NGS samples’ precious nature. Therefore, we offer Roche Sample Prep Solutions, from sample collection to library quantification for different sample types and sequencing applications that are proven, simple and complete.

If you would like to share your design on this page, please contact your local Roche sales representative. In case you are interested in fully verified and validated panels that are also off-the-shelf available, such as the KAPA HyperExome Probes or the KAPA HyperCap Fixed Panels, please visit the respective pages. All Design Share panels are compatible with NAVIFY® Mutation Caller for confident germline SNV/Indel analysis.

Hereditary Genetics & Oncology

  • Organism: Human

  • Genome Build: HG38

  • Design FilesOriginal build (hg38)Translated (hg19)

  • NAVIFY Mutation Caller: Analysis file package
  • Performance Data: Available, please contact your local Roche office.
  • Collaborator: Dr Jason Park

  • Specifications/Details: The Inherited Disease Panel covers > 4100 genes and regions associated with inherited disease with a capture target size of 12.3 Mb. It was originally designed in collaboration with Dr Jason Park and scientists at Roche Sequencing with proven design expertise, who later updated its ClinVar content. 

  • Ordering Information
    Product Type: KAPA HyperChoice Probes
    Internal Reference # (IRN) 1000004873

  • Material Numbers & Pack Sizes:

    KAPA HyperChoice MAX 40Mb starting from 24 reaction packs:

    09053352001 for 24 rxn
    09053379001 for 48 rxn
    09053387001 for 96 rxn
    09053395001 for 192 rxn
    09053409001 for 384 rxn

    Larger reaction pack sizes are also available

    Contact Us

  • Organism: Human
  • Genome Build: HG38
  • Design Files:  Original build (hg38), Translated (hg19)
  • NAVIFY Mutation Caller: Analysis file package
  • Performance Data: Available, please contact your local Roche office.
  • Specifications/Details: The Sudden Cardiac Death Panel covers 152 genes and regions associated with cardiovascular conditions with a capture target size of 772 Kb. It was designed by Roche scientists with proven design expertise and guidance from publications and industry experts.
  • Ordering Information:
    Product Type: KAPA HyperChoice Probes
    Internal Reference # (IRN) 1000004863
  • Material Numbers & Pack Sizes:
    KAPA HyperChoice MAX 3Mb T3 starting from 12 reaction packs:
    09052895001 for 12 rxn
    09052909001 for 24 rxn
    09052917001 for 48 rxn
    09052925001 for 96 rxn
    09052933001 for 192 rxn
    09052941001 for 384 rxn
    Larger reaction pack sizes are also available

    Contact Us
  • Organism: Human
  • Genome Build: HG38
  • Design File: Original build (hg38)Translated (hg19)
  • NAVIFY Mutation Caller: Analysis file package
  • Performance Data: Available, please contact your local Roche office.
  • Specifications/Details: The Neurodegeneration Panel covers over 98 genes and regions associated with neurodegenerative disorders with a capture target size of 335 Kb. It was designed by Roche scientists with proven design expertise and guidance from publications and industry experts. 
  • Ordering Information
    Product Type: KAPA HyperChoice Probes
    Internal Reference # (IRN) 1000004883
  • Material Number & Pack Sizes:
    KAPA HyperChoice MAX 3Mb T1 starting from 12 reaction packs:
    09052585001 for 12 rxn
    09052593001 for 24 rxn
    09052607001 for 48 rxn
    09052615001 for 96 rxn
    09052623001 for 192 rxn
    09052631001 for 384 rxn
    Larger reaction pack sizes are also available

    Contact Us
  • Organism: Human
  • Genome Build: hg19
  • Design File: Original build (hg19)Translated (hg38)
  • NAVIFY Mutation Caller: Analysis file package
  • Performance Data: Available, please contact your local Roche office.
  • Collaborator: Prof. Zdenek Kleibl
  • Publication: Validation of CZECANCA (CZEch CAncer paNel for Clinical Application) for targeted NGS-based analysis of hereditary cancer syndromes. PLoS One. 2018 Apr 12;13(4):e0195761.
  • Specifications/Details: The Hereditary Cancer Panel covers 226 genes and regions commonly associated with hereditary cancer syndromes with a capture target size of 744 Kb. It was designed by Prof. Zdenek Kleibl and Roche scientists with proven design expertise.
  • Ordering Information
    Product Type: KAPA HyperChoice Probes
    Internal Reference # (IRN) 1000007813
  • Material Number & Pack Sizes:
    KAPA HyperChoice MAX 3Mb T3 starting from 12 reaction packs:
    09052895001 for 12 rxn
    09052909001 for 24 rxn
    09052917001 for 48 rxn
    09052925001 for 96 rxn
    09052933001 for 192 rxn
    09052941001 for 384 rxn
    Larger reaction pack sizes are also available

    Contact Us

 

Metabolic Disease Research

  • Organism: Human

  • Genome Build: HG38

  • Design File: hg38

  • NAVIFY Mutation Caller: Analysis file package

    Performance Data: Available, please contact your local Roche office.

  • Specifications/Details: The Human mtDNA Panel covers the Human mitochondrial genome with a primary target size of 16 Kb. It was designed by Roche scientists with proven design expertise.

  • Ordering Information
    Product Type: KAPA HyperChoice Probes
    Internal Reference # (IRN) 1000005603

  • Material Numbers & Pack Sizes:

    KAPA HyperChoice MAX 0.5Mb T1 starting from 12 reaction packs:


    09052143001 for 12 rxn
    09052151001 for 24 rxn
    09052160001 for 48 rxn
    09052178001 for 96 rxn
    09052186001 for 192 rxn
    09052194001 for 384 rxn
    Larger reaction pack sizes are also available


    Contact Us