Targeted sequencing enables researchers to enrich specific genes, exons and/or other genomic regions to allow sequencing reads to be dedicated to only the regions that are of interest, which results in time and cost savings.1 To enrich specific target regions for next-generation sequencing (NGS) and bioinformatic analysis, hybridization or capture-based target enrichment is a method frequently used. This technique can be applied to single nucleotide polymorphism (SNP) detection, insertion/deletion (indel) detection, copy number variation (CNV) detection and structural variation detection.
Now available is Roche’s new KAPA Target Enrichment Portfolio — KAPA HyperExome, KAPA HyperChoice and KAPA HyperExplore probes. Our industry-leading selection of probes will now offer higher performance, higher probe fidelity and in-solution hybridization capture, as well as longer probes with fixed length.
The KAPA HyperExome probes will replace SeqCap EZ Prime Exome Probes, which will be supported until the end of March 2022.