Cancer research solutions

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Assays	Product	Benefits
AVENIO NGS Oncology Assays*	AVENIO ctDNA Analysis Kits AVENIO ctDNA Targeted Kit Tumor profiling AVENIO ctDNA Expanded Kit Expanded tumor profiling AVENIO ctDNA Surveillance Kit Longitudinal tumor burden monitoring AVENIO Tumor Tissue Analysis Kits AVENIO Tumor Tissue Targeted Kit Tumor profiling AVENIO Tumor Tissue Expanded Kit Expanded tumor profiling AVENIO Tumor Tissue Surveillance Kit Longitudinal tumor burden monitoring AVENIO Tumor Tissue CGP Kit Comprehensive Genomic Profilingᐩ	Portfolio of assays provide flexibility to match the right test to the right research goal. Tumor tissue and liquid biopsy assays with matching gene panels Flexibility to match the right assay to the right research goal Includes genes in the U.S. National Comprehensive Cancer Network (NCCN) Guidelines¹ All four mutation classes (SNVs, inDels, fusions and CNVs) in a single assay Exceptional analytical performance backed by robust data^2,3 End-to-end workflow from extraction to analysis and reporting in five days Detects genomic signatures: TMB, MSI and LOHᐩ

Assays

Product

Benefits

AVENIO NGS Oncology Assays*

AVENIO ctDNA Analysis Kits

AVENIO ctDNA Targeted Kit
Tumor profiling

AVENIO ctDNA Expanded Kit
Expanded tumor profiling

AVENIO ctDNA Surveillance Kit
Longitudinal tumor burden monitoring

AVENIO Tumor Tissue Analysis Kits

AVENIO Tumor Tissue Targeted Kit
Tumor profiling

AVENIO Tumor Tissue Expanded Kit
Expanded tumor profiling

AVENIO Tumor Tissue Surveillance Kit
Longitudinal tumor burden monitoring

AVENIO Tumor Tissue CGP Kit
Comprehensive Genomic Profilingᐩ

Portfolio of assays provide flexibility to match the right test to the right research goal.
Tumor tissue and liquid biopsy assays with matching gene panels
Flexibility to match the right assay to the right research goal Includes genes in the U.S. National Comprehensive Cancer Network (NCCN) Guidelines¹
All four mutation classes (SNVs, inDels, fusions and CNVs) in a single assay
Exceptional analytical performance backed by robust data^2,3
End-to-end workflow from extraction to analysis and reporting in five days
Detects genomic signatures: TMB, MSI and LOHᐩ

⁺ Only applicable to AVENIO Tumor Tissue CGP Kits

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Workflow Step	Product	Benefits
Sample QC	KAPA NGS FFPE & QC KIt	Reliable quantification and quality assessment of low-input or FFPE samples to optimize library construction yields and workflows
Target Enrichment	KAPA HyperCap KAPA HyperExome KAPA HyperChoice (human designs) KAPA HyperExplore (non-human designs) KAPA HyperCap Oncology Panel KAPA HyperCap Heredity Panel KAPA SARS-CoV-2 Panel	Reduce sequencing costs and save time with superior capture uniformity Demonstrated design expertise, 10+ years of experience Reliably enrich challenging, previously inaccessible genomic regions
	KAPA HyperPETE KAPA HyperPETE Choice / Explore (human designs) KAPA HyperPETE Choice / Explore RNA (human designs) KAPA HyperPETE Pan Cancer Panel KAPA HyperPETE Hot Spot Panel KAPA HyperPETE Hereditary Oncology Panel KAPA HyperPETE Lung Cancer Fusion Panel	Save valuable time with an efficient, single-day, automatable workflow Achieve superior performance and coverage uniformity Uncover critical genomic information from a wide variety of sample types, including FFPET and cfDNA Detect all major somatic variants in cfDNA, FFPE, and RNA samples, including SNVs, short indels, CNVs, MSI, and fusion transcripts (novel and known)
	KAPA HyperCap Workflow v3	Streamline targeted sequencing with HyperCap workflow v3
Library Preparation	KAPA DNA Library Preparation Kits KAPA Library Preparation Accessories KAPA Adapters KAPA Library Amplification Kits KAPA Library Quantification Kits	Tailor your library preparation workflow to your needs with a portfolio of streamlined, versatile solutions that reliably preserve sample sequence complexity for improved sequencing outcomes

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Instruments	Product	Benefits
Sample Collection	AVENIO Millisect System	Maximize clinical utility of tissue samples by identifying mutations missed with manual dissection and reducing false negative rates^3,4 Increase dissection efficiency and optimize results by capturing clinically relevant cells³ Improve lab workflow and minimize demands on staff by ensuring consistent sample capture through an automated, digitally assisted process