NimbleDesign is a free online tool that enables you to quickly and easily design custom SeqCap® EZ Choice or HEAT-Seq® Choice Designs. The NimbleDesign software uses our empirically optimized probe database and design process, derived from years of design experience, for proven probe selection. This web-based application provides you 24/7 access with easy setup in designing your probe sets for human and non-human research applications.

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Benefits of NimbleDesign Software

  • Intuitive User Interface from Start to Finish: Follow clear, simple instructions to create one design or many in parallel for your target region of choice
  • Flexible Input: Choose from a broad list of commonly used gene identifiers to retrieve annotation for your review. In addition to coordinate entry, input a long list of gene names or look up genes via the search tool to add target regions for your design
  • Comprehensive Design Features: Design to target  human or mouse genomes with the ability to create or modify DNA or RNA designs

Product Highlights

Rapid turnaround time for custom designs

  • Easy step-by-step instructions for selecting your genomic targets
  • Ability to develop multiple designs in parallel for quick review and selection of the best design within a few hours


Convenience with an easy workflow

  • 24/7 access with easy setup for creating and approving your custom target enrichment designs


Discovery of more variants through our proven industry-leading design algorithm*

  • Superior capture efficiency leveraging years of  design informatics expertise and 2.1M overlapping probes to ensure the highest uniform coverage

Rapid configuration of custom molecular inversion probe (MIP) panels

  • Data-driven HEAT-Seq Choice  databases to create custom panels of up to 20,000 probes for human genetics  research applications

*Data on file.