Fragmented Data: The information is highly fragmented requiring review of multiple public sources in order to make a proper interpretation.
Time Intensive: Annotation and interpretation is very time consuming and requires significant due diligence to verify that the assessment is based on the most up-to-date information.
Complex Analysis: Integrating the results of functional studies, the outcomes of clinical trials, medical guideline recommendations and drug labels, and then summarizing this so that it's readily comprehensible to the clinician receiving a clinical report is challenging.
Sample Volume Increase: With growing clinical utility evidence supporting NGS testing, clinical labs are projecting an increase in adoption of NGS tests.
Larger Panels: As sequencing cost continues to decrease and more actionable variants are discovered there will be a trend to move towards using larger panels.