AVENIO Millisect System

AVENIO Millisect System



The AVENIO Millisect System is an automated, high-performance tissue dissection system that enables precise and consistent recovery of formalin-fixed paraffin-embedded (FFPE) tissue areas of interest for molecular pathology. The system is optimized to fit easily into a variety of clinical workflow configurations, improves diagnostic testing results by reducing false negatives, and can help you efficiently extract more clinically relevant information from every sample.

AVENIO Millisect System at The Ottawa Hospital

Dr. Bryan Lo at The Ottawa Hospital in Canada talks about the need to precisely isolate tumor content as tumor biopsies get smaller in the future. Learn how the AVENIO Millisect System can improve molecular diagnostics laboratory workflow.

  • Optimize tumor yield and minimize contamination with precise tissue dissection1
  • Maximize actionable tumor information and reduce false negative results1,2
  • Improve laboratory workflow by ensuring sample acquisition is efficient, consistent3 and traceable.
AVENIO Millisect System

Product Highlights

Digital annotation
  • Allows definition of multiple Areas of Interest (AOIs) on a single slide, without limits on geometry
  • Digitally-assisted alignment to reference slide for up to 4 serial slides
  • Intuitive software interface to guide user annotations
Automated milling
  • Faster process with fewer steps and no pre-staining
  • Precise milling displaces tissue AOIs as small as 250 μm using a rotating action
  • Automated consumable loading, filling and unloading
Gentle recovery
  • Hands-free process minimizes potential for contamination
  • Capillary action used to lift and recover AOIs after milling
  • No risk of burning or losing sample with gentle, non-laser dissection
Comprehensive reporting
  • Electronic report file, including images, annotations and notes, exportable as a PDF
  • Pre-and post-dissection image capture
  • Barcode scanning for improved traceability
AVENIO Millisect System
AVENIO Millisect System
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  1. Geiersbach K et al. Cancer Genet. 2016;209(1-2):42-49. 2.
  2. Gustafson H et al. Integr Cancer Sci Therap. 2016;3(4):500-503.
  3. Data on file.


  • Instrument footprint (W x D x H)

    48 x 33 x 57 cm (19 x 13 x 22 in)

  • Instrument input power requirements

    100-240V ~ 1.5-0.75A 50-60Hz

  • Instrument weight

    21 kg (46 lbs.)

  • PC foot print (W x D x H)

    50 x 21 x 40 cm (20 x 9 x 16 in)

  • PC input power requirements

    100-240V ~ 2.9A 50-60Hz

  • PC weight

    8.1 kg (17.8 lbs)

  • Safety and emission

    ETL, EN

  • Regulatory

    US-IVD FDA Class 1 (510K exempt), CE-IVD


  • Camera resolution

    14 MP

  • Optical Zoom


  • Digital Zoom



  • Stage area

    9,000 mm square

  • Stage accuracy

    5 μm


  • Dissection resolution

    ≈300 μm

  • Recovery efficiency

    Equivalent to manual dissection

  • Dissection time*

    2 minutes for 1 slide
    Up to 7 minutes for 4 slides

*Depending on number of annotations - estimated time based on current data


  • Milling tip – small blade (yellow)

    ≈250 μm

  • Milling tip – medium blade (green)

    ≈525 μm

  • Milling tip – large blade (blue)

    ≈725 μm

  • Dissection fluid volume (ejected)

    ≈270 μL

  • Fill station volume

    ≈4 mL

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View Full Table


Roche Cat. No Description Pack Size
AVENIO Millisect Instrument, Base
AVENIO Millisect Instrument, Head
AVENIO Millisect PC
AVENIO Millisect Milling Tips S
48 Pack
AVENIO Millisect Milling Tips M
48 Pack
AVENIO Millisect Milling Tips L
48 Pack
AVENIO Millisect Fill Station
16 Pack
VANTAGE BCR - Handheld - Honeywell*  
VANTAGE BCR - Stand Rigid - Honeywell*
VANTAGE BCR - Stand Flexible - Honeywell*
*Optional Barcode Scanner for purchase
To place an order or ask a question
Contact us