SeqCap Epi Choice Probes for Epigenetic Analysis

Discontinued SeqCap Portfolio

SeqCap Epi Choice Probes have been discontinued. Our new KAPA Target Enrichment Portfolio is now available and contains our new KAPA HyperExome, as well as our new custom probes, KAPA HyperChoice and KAPA HyperExplore. For additional questions, please contact your regional sales representative.

Overview

SeqCap® Epi Choice Probes enable targeting of selected human genomic regions from bisulfite-treated genomic DNA in a single workflow. The probes are customizable probe pools that can target both strands of bisulfite-treated human genomic DNA for targets up to 90Mb.

Benefits of SeqCap Epi Probes

Efficient discovery of differential methylation

Target up to 90Mb of genomic regions to obtain better depth of coverage and higher resolution of differential methylation compared to whole genome bisulfite sequencing

Optimized design and workflow to effectively conserve epigenome complexity

Obtain superior target enrichment performance with an advanced design algorithm coupled with over 2.1 million long oligonucleotide probes
Observe methylation changes on both strands while preserving the ability to decipher between SNPs vs. methylation events, with an industry-leading sample input of just 1µg*

Maximized epigenetic discovery

Reduce the amount of sequencing needed to discover and validate methylation events potentially responsible for disease by focusing on your region of interest

Custom Designs

NimbleDesign, our free online tool, enables you to quickly and easily design custom SeqCap EZ Choice, SeqCap EZ Choice XL or HEAT-Seq® Choice Designs for human and non-human research applications. Learn more about the NimbleDesign software for custom target enrichment designs.

Benefits of SeqCap Epi Probes

Efficient discovery of differential methylation

Target up to 90Mb of genomic regions to obtain better depth of coverage and higher resolution of differential methylation compared to whole genome bisulfite sequencing

Optimized design and workflow to effectively conserve epigenome complexity

Obtain superior target enrichment performance with an advanced design algorithm coupled with over 2.1 million long oligonucleotide probes
Observe methylation changes on both strands while preserving the ability to decipher between SNPs vs. methylation events, with an industry-leading sample input of just 1µg*

Maximized epigenetic discovery

Reduce the amount of sequencing needed to discover and validate methylation events potentially responsible for disease by focusing on your region of interest

Custom Designs

NimbleDesign, our free online tool, enables you to quickly and easily design custom SeqCap EZ Choice, SeqCap EZ Choice XL or HEAT-Seq® Choice Designs for human and non-human research applications. Learn more about the NimbleDesign software for custom target enrichment designs.