HEAT-Seq® Choice Designs enable you to build custom designs of varying length (between 140 to 27,343 probes) choosing from our database. The probes are empirically tested and balanced, and target thousands of genes associated with human inherited disease.
The Roche Sequencing Solutions HEAT-Seq Probe database, built on our expertise and proprietary technology, makes customization of challenging probe construction (especially for Molecular Inversion Probes (MIPs)) simpler. Selecting probes from our database allows for peace of mind against poor uniformity concerns, dead or poison probes, or creating the probe pools from many individual oligos. Custom HEAT-Seq Choice designs are made using NimbleDesign software.