Overview

SeqCap® EZ Choice Probes allow for enrichment of genomic regions of interest up to 7 Mb for human resequencing studies with an automation-friendly workflow. SeqCap® EZ Choice Probes are replaced by SeqCap® EZ Prime Choice Probes, which provide improved GC coverage compared to SeqCap EZ Choice Probes.

Benefits of SeqCap EZ Choice Enrichment Kits

  • Capture up to 7 Mb custom regions with a single design utilizing up to 2.1 million probes
  • Achieve uniform and high performance capture and save on sequencing costs
  • Capture more target regions to identify more variants compared to other enrichment methods*
  • Obtain higher coverage of target regions with our advanced repeat masking methods
  • Combine with KAPA's library preparation products to create the HyperCap Workflow v2.0 for a fully integrated sample preparation solution.

Minimize sequencing costs through efficient multiplexing

Sample Multiplex Capabilities
Coverage Illumina HiSeq (34 Gb*) Illumina MiSeq (4 Gb*)
75x 14 Samples 2 Samples
100x 12 Samples 1 Sample
150x 7 Samples -
*Estimates for sequencing throughput per lane are based on Manufacturer's specifications

Design your own targets

NimbleDesign, our free online tool, enables you to quickly and easily design custom SeqCap EZ Prime Choice, SeqCap EZ Prime Developer Probes, SeqCap EZ Prime Choice XL or HEAT-Seq® Choice Designs for human and non-human research applications. Learn more about the NimbleDesign software for custom target enrichment designs.

Sample throughput multiplexing. Illustrated at 75x, 100x, and 150x coverage rates with 90% bases covered using Illumina 2x76 bp reads on either a HiSeq or MiSeq instrument.

  *Data on file.