Library Preparation Accessories


Library preparation for next generation sequencing (NGS) involves several key steps: fragmentation of nucleic acids to required lengths, addition of platform-specific adapters, optional library amplification, and library quantification and/or normalization. In both DNA and RNA (cDNA) library construction workflows, it is often necessary to select for fragments of the appropriate size. Removing unused adapters, primers and dimers is critical prior to sequencing. Adapter and bead quality and performance can have a profound impact on the outcome of library construction and sequencing, particularly when working with low-input and challenging samples.

Roche Sequencing Solutions offers high-quality adapters and beads that are functionally tested in NGS library construction workflows, and meet strict QC specifications. KAPA Adapters and KAPA Cleanup Beads are available as stand-alone products to offer you maximum flexibility.

KAPA Cleanup Beads

KAPA Cleanup Beads, which includes KAPA HyperPure Beads and KAPA Pure Beads, offer tunable and highly consistent bead solution for reaction purification and size selection in DNA and RNA next-generation (NGS) library construction workflows.

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High-quality adapters for multiplexed sequencing on 2- and 4-channel Illumina® instruments, with patterned or non-patterned flow cells. Compatible with all KAPA Hyper library preparation kits, the HyperCap Workflow with Roche Universal Blocking Oligos, and PCR-free workflows.

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