Hybridization-Based Target Enrichment

Next-generation sequencing (NGS), with its ability to process hundreds of millions of DNA templates in parallel, has increased sequencing throughput and diminished sequencing costs tremendously¹. However, whole genome sequencing is still expensive and does not provide the precision and depth of information required to decipher the roles of individual genes in complex diseases or afford the ability to investigate rare and low-frequency genetic variants. A more cost-effective way is to focus on specific regions of interest using target enrichment strategies. Target enrichment allows focusing of sequencing resources, which leads to reduced cost and simplified analysis².

Combining more than a decade of design experience with an improved manufacturing technology, the KAPA Target Enrichment Portfolio unlocks the potential of your starting material to bring you the answers you seek.

• Superior capture uniformity for lower sequencing costs/time
• Demonstrated design expertise for targeting difficult-to-capture sequences
• Outstanding single-vendor support across the entire workflow