Building on over 10 years of design expertise, Roche is pleased to introduce the KAPA Target Enrichment Portfolio. These new probes for hybridization-based target enrichment are available in the new KAPA HyperExome* or in Custom Panels* that you develop using HyperDesign*, our new online development tool.

Our KAPA Target Enrichment Portfolio probes and updated HyperCap v3 workflow offer significant benefits and improvements compared to SeqCap EZ probes, including:

  • Demonstrated design expertise for targeting difficult-to-capture sequences
  • Superior capture uniformity for lower sequencing costs/time
  • Outstanding single-vendor support across the entire workflow
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  • Identify multiple variants of SARS-CoV-2 in a single reaction*
  • Cover more of the SARS-CoV-2 genome & identify viral sequence from low viral copy numbers
  • Save valuable time with hybridization as short as 1 hour

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Increase sequencing efficiency with KAPA HyperExome

  • Optimize sequencing throughput with our compact ~43 Mb design
  • Achieve better coverage compared to Supplier X, especially with deeper sequencing
  • Increase coverage uniformity across a broad range of GC content

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Easily design custom panels online

HyperDesign is a new online tool that uses Roche’s renowned algorithm for probe design and selection, enabling you to customize your target enrichment panels to meet the unique needs of your research. In addition, Roche’s Support Scientists are ready to help you with design planning and optimization.

KAPA HyperChoice

Capture up to 200 Mb of human targets.

KAPA HyperExplore

Capture up to 200 Mb of non-human targets.


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Target-enriched RNA-seq for SARS-CoV-2 surveillance & genome analysis

In this webinar we:

  • Review the HyperCap Workflow using the KAPA SARS-CoV-2 panel
  • Describe an accelerate workflow with a standard 1 hour hybridization
  • Discuss optional workflow modifications to increase SARS-CoV-3 reads
  • Present performance data for samples containing varying amounts of SARS-CoV-2 RNA in background of human RNA
  • Show that the KAPA SARS-CoV-2 TE panel can detect mutations from multiple strains within a single reaction


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Request Evaluation

Contact your local Roche representative about evaluating KAPA Target Enrichment.