KAPA RNA HyperPrep Kit with RiboErase (HMR)


The KAPA RNA HyperPrep Kit with RiboErase (HMR) targets and depletes rRNA using DNA probes and RNase H to provide improved coverage of transcripts of interest, including precursor mRNAs and important regulatory species, such as noncoding RNAs. Sequencing of rRNA-depleted total RNA samples provides a more comprehensive representation of the whole transcriptome. This kit is suitable for total RNA input from human, mouse and rat species only.

Benefits of KAPA RNA HyperPrep Kits with RiboErase

• rRNA depletion and purification in ~2.5 hours

• Robust performance across different sample types and input amounts

• High success rates with low-input and degraded samples

• Qualified automation methods


Generate high-quality libraries from degraded samples

  • Prepare libraries with as little as 25 ng  FFPE RNA samples, depending on total RNA quality
  • Achieve low duplication rates and highly efficient, reproducible rRNA removal with degraded samples
  • Identify more unique transcripts and genes with equivalent sequencing