1. Roche Sequencing | United States - English
  2. NGS Oncology Assays
  3. AVENIO ctDNA Analysis Kits
  4. AVENIO ctDNA Targeted Kit – Tumor Profiling

AVENIO ctDNA Targeted Kit

Overview

The AVENIO ctDNA Targeted Kit is a next-generation sequencing (NGS) liquid biopsy assay that contains 17 genes , including those in U.S. National Comprehensive Cancer Network (NCCN) Guidelines.1  The Targeted panel may be used for pan-cancer research applications, but is specially optimized for lung cancer and colorectal cancer (CRC).  The AVENIO ctDNA Targeted Kit is an efficient tumor profiling solution.

Features and Benefits of AVENIO ctDNA Targeted Kit

  • Includes genes in the U.S. National Comprehensive Cancer Network (NCCN) Guidelines1
  • All four mutation classes (SNVs, indels, fusions and CNVs) in a single assay
  • Exceptional analytical performance supported by integrated digital error suppression (iDES) strategies combining molecular barcodes with in silico error suppression techniques2,3
  • Includes reagents, bioinformatics and software
  • Streamlined, end-to-end workflow from extraction to analysis and reporting in five days

Product Highlights

Accurate detection of mutations with high sensitivity and specificity2,3

  • >99% sensitivity for for all classes of mutations
  • >99% positive predictive value (PPV)  for all classes of mutations

 

View performance data showing >99% PPV for all four classes of mutations from 10-50 ng input DNA using the AVENIO ctDNA Targeted Kit.

Profiling of a broad array of genes with a single assay kit

  • 17 assay targets in a single panel

 

View AVENIO ctDNA Targeted Kit assay targets.

A portfolio of NGS liquid biopsy assays  

The AVENIO ctDNA Targeted Kit is one of three assays in the AVENIO ctDNA assay portfolio. Learn more about the 77-gene AVENIO ctDNA Expanded Kit for expanded tumor profiling or the 197-gene AVENIO ctDNA Surveillance Kit for longitudinal tumor burden monitoring.

References

1. National Comprehensive Cancer Network. October 15, 2016.

2. Newman AM, Lovejoy AF, Klass DM, et al., Integrated digital error suppression for improved detection of circulating tumor DNA. Nature Biotechnology. 2016; 34(5):547 – 555. doi:10.1038/nbt.3520.

3. Data on file.

Research Use Only. Not for use in diagnostic procedures.
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