Roche Sequencing at the ASHG Virtual Meeting 2021, October 18 - 22

Roche Sequencing at the ASHG Virtual Meeting 2021

We’re excited to be featuring three new additions to our extensive toolkit for next-generation sequencing (NGS) at the 2021 ASHG Virtual Meeting:

  1. KAPA HyperPETE,* a novel target enrichment technology for DNA and RNA that is designed to combine the performance of hybrid capture with the short turnaround time of amplicon-based workflows
  2. KAPA EvoPlus Kits* for enzymatic fragmentation-based library preparation, developed to bring new levels of performance, convenience, and scalability to germline applications, such as WGS, WES, and other target-enriched sequencing
  3. The AVENIO Edge System* for fully automated sample preparation, including library prep, target enrichment, library quant, and pooling 

Stop by our booth, we’d love to chat and hear all about what you’ve been up to! And, we’ll have links to our ASHG lightning talk, CoLabs, new product offerings, video resources and more… as well as additional information about other new and existing products.


Join Us

KAPA EvoPlus Kits*: Enzymatic fragmentation-based library preparation designed to bring new levels of performance, convenience, and scalability

Date: Wednesday, October 20th
Time: 12:45 - 1pm EDT (live)
Location: Clickable from the Roche Sequencing & Life Science Booth or from the main networking page

This presentation will include:

  • An overview of the key technological innovations of KAPA EvoPlus* Kits designed to enable a convenient and accelerated workflow that reduces the opportunity for human error
  • Preliminary data on KAPA EvoPlus* performance with whole genome sequencing and whole exome sequencing using DNA extracted from cell lines and formalin-fixed paraffin-embedded tissue (FFPET)

Speaker: Albert Abrie, PhD
Principal Scientist II
Roche Diagnostics

KAPA HyperPETE*: A Novel Primer Extension Target Enrichment Solution for Rapid and Reliable Variant Detection Results

Date: Thursday, October 21st
Time: 3:00 - 3:30 pm EDT (live)
Location: Clickable from the Roche Sequencing & Life Science Booth or from the main networking page

This presentation will include:

  • An overview of KAPA HyperPETE* Panel technology
  • Preliminary data for KAPA HyperPETE*, featuring off-the-shelf panels for somatic oncology--including data for somatic cfDNA, somatic tissue DNA, and somatic tissue RNA

Speaker: Brian Godwin
Director, Sample Prep Reagent Development
Roche Sequencing Solutions

Demonstration: The AVENIO Edge System* — Automated System for NGS Library Prep, Target Enrichment, QC, and Pooling

Available on-demand: from the Roche Sequencing & Life Science Booth or the on-demand content section of the meeting

The AVENIO Edge System* is Roche's fully automated system for NGS library preparation, target enrichment, library QC, and sample pooling. With integrated workflows, trusted KAPA reagents, and end-to-end connectivity, the AVENIO Edge System* is designed to enable reliable, high-quality results without the need for constant instrument monitoring. In this demo, we will highlight key features and benefits of the AVENIO Edge System*, and demonstrate the simplicity of system setup by sharing the step-by-step process for a user-defined library preparation workflow.


Speaker: Scott Verrow
Senior Automation Support Scientist
Roche Sequencing and Life Science

Introduction of a Walk-away Automated Roche NGS Workflow Solution: Integrated KAPA Library Preparation, KAPA Target Enrichment and the AVENIO Edge* Instrument

Authors: Persis Wadia, Edwin Malfarta, Alva Liang, Joshua Lefkowitz, Smriti Sharma, Durga Emani, Patrick Ton, Benjamin Morck, Tim Williams, Jennifer Dasgupta,Arash Fararooni, Arrezo Moghaddasi, Arafat Al-Ariemy, Michael Pintor, Bill LaRochelle, Neda Razavi, Pierre-Luc Janvier. 
Roche Sequencing Solutions, Pleasanton


Viewing details:
Oct 18th, Poster Session D
3.30-4.30pm, Poster Number 3529

Featured Products

Picture of a DNA strand in blue and green colors

NEW KAPA HyperPETE* Target Enrichment Portfolio for NGS

Combine the performance of hybrid capture with the simplicity and short turnaround time of amplicon-based workflows. KAPA HyperPETE* is optimized to detect all major somatic variants in cfDNA, FFPE, and RNA samples, including SNVs, short indels, CNVs, MSI, and fusion transcripts (novel and known).

  • Interrogate difficult regions by leveraging Roche’s expertise in panel content and design
  • Save valuable time and resources with single-day, automatable workflows
  • Increase analysis efficiency with focused, high-uniformity panel design and no need for primer trimming
  • Preserve precious samples and improve sensitivity by avoiding the need to split panels
Learn More

NEW KAPA EvoPlus Kits*

Engineered to reduce the performance challenges inherent in existing enzymatic fragmentation methods (e.g., sequencing artifacts), KAPA EvoPlus kits* combine performance, inhibitor tolerance, scalability, and ease of use in a streamlined workflow for whole-genome, exome, and target enrichment sequencing applications.

  • Save time and effort with a streamlined workflow and choice of flexible automation-friendly formats
  • Minimize sequencing artifacts (chimeras, soft clips, SSAR's) inherent in existing enzymatic fragmentation methods 
  • Reduce fragmentation optimization efforts with enhanced EDTA and inhibitor tolerance
  • Achieve optimal results across various sample types, including FFPET, cfDNA, and cell lines
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KAPA Library Prep (RNA, DNA and custom kits)

  • KAPA RNA HyperPrep Kit portfolio for RNA library prep provides single-day, single-tube library preparation, yielding high-performance libraries even from low-input and degraded samples. Choose solutions for mRNA enrichment and for the depletion of rRNA, globin mRNA, and/or user-defined targets.
  • KAPA HyperPrep Kit and HyperPlus Kit for DNA library prep offer high performance with WGS and targeted sequencing, PCR-free workflows, and high-quality data, even from low-quality samples.
  • Solutions for custom and/or automated library prep. If your moderate- to high-throughput library preparation workflows would be enhanced by library kit customization, reach out to our team of Genome Specialists so we can find the right solution to meet your needs.
Learn More

NEW AVENIO Edge System*

  • Fully automated system for Roche Sequencing NGS workflows covering KAPA library prep, target enrichment, and library quantification.


Learn More

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