SeqCap EZ Choice XL

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Product Overview

Targeting, enriching, and sequencing specific genomic regions of interest is key to advancing our knowledge of genomic variation and its relationship to disease. Researchers commonly use targeted resequencing to investigate causative mutations in disease associated regions, novel mutations present in Mendelian disease, and to detect coding variants in genes. SeqCap EZ Choice Library provides researchers with an easily automated, multiplex friendly tool to prepare samples for human targeted resequencing studies. Create your custom SeqCap EZ Choice Design to discover more variants that matters in your research.

7Mb-200Mb human genomic regions
Description Target Regions Catalog Number Pack Size
SeqCap EZ Choice XL 7Mb-200Mb human genomic regions 06740260001 4 Reactions
SeqCap EZ Choice XL 7Mb-200Mb human genomic regions 06266363001 12 Reactions
SeqCap EZ Choice XL 7Mb-200Mb human genomic regions 06266371001 24 Reactions
SeqCap EZ Choice XL 7Mb-200Mb human genomic regions 06266380001 48 Reactions
SeqCap EZ Choice XL 7Mb-200Mb human genomic regions 06266398001 96 Reactions
SeqCap EZ Choice XL 7Mb-200Mb human genomic regions 06266401001 384 Reactions
SeqCap EZ Choice XL 7Mb-200Mb human genomic regions 06266517001 960 Reactions
06266401001
06266401001

Please Contact Us for ordering and questions

New! SeqCap EZ HyperCap Workflow User's Guide v1.0 

The SeqCap EZ system can now be used with the SeqCap EZ HyperCap Workflow. The HyperCap workflow provides an integrated, application-specific approach for efficient, streamlined and automatable targeted sequencing solution. It combines high-efficiency KAPA Hyper Prep and KAPA HyperPlus Library Preparation Kits with performance-optimized SeqCap EZ capture protocol.

For life science research only. Not for use in diagnostic procedures.


Product Description

SeqCap EZ Choice Kits enable enrichment of custom regions of interest from 7 Mb to 200 Mb.

Benefits

  • Achieve uniform capture, and save on sequencing costs. The NimbleGen Sequence Capture design algorithm utilizes up to
  • 2.1 million probes and ensures high-performance capture.
  • Capture up to 200 Mb custom regions with a single design.
  • Identify more mutations. More complete coverage of target regions with advanced repeat masking methods.


NimbleDesign_Figure_2

Figure 1: Design comparison between SeqCap EZ Choice Enrichment System and Competitor A Design Software. A 3.51Mb region on Chromosome 18 was targeted to compare probe coverage across design platforms. Roche NimbleDesign probes covered 79.3% of the target region (2.79 Mb of target) compared to a coverage of 50.2% (1.77 Mb of target) by Competitor A design software. Note: Probe design used standard design parameters for both NimbleDesign and Competitor A software. Coordinate files from each design was uploaded to SignalMap software to obtain coverage file illustrated above. About 1.05 Mb of coverage space was unique to the NimbleDesign platform that was not covered by the Competitor A software.


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