What's next for whole genome sequencing?

Moving from research to diagnostics and beyond

As the throughput of next-generation sequencers continues to improve and the cost of reagents declines, whole-genome sequencing (WGS) becomes increasingly cost-effective, making it a realistic possibility for use in a clinical setting. In this webinar, our speakers will discuss how they see WGS evolving as it moves closer to the clinic, highlighting the pros and cons of a whole-genome approach versus a targeted approach. They will also address the hurdles currently slowing implementation of WGS in the clinic, including the lack of reimbursement from medical insurance, the need to achieve the desired sequencing depth in the most cost-effective manner, and how best to manage the huge amounts of data generated.

During the webinar, the speakers will discuss:

  • The potential of WGS for cancer diagnosis
  • Challenges and solutions for research applications of WGS
  • The improved diagnostic utility of WGS compared to the current standard-of-care genetic testing.


Christian Marshall, Ph.D.
The Hospital for Sick Children
Toronto, Canada


Shashikant Kulkarni, M.S., Ph.D., FACMG
Baylor College of Medicine
Houston, TX


Sean Sanders, Ph.D.
Washington, DC